Very interesting! I stand corrected... (huh, I must have dozed off during that part of the lecture... I better tell my cohort who also agreed with me on the subject!Brakecheck wrote:Xaque, I did a little research and this is what I came up with.
The causes of anaphylaxis are divided into two major groups:
...Non-IgE mediated: These reactions, the so called "anaphylactoid" reactions, are similar to those of true anaphylaxis, but do not require an IgE immune reaction. They are usually caused by the direct stimulation of the mast cells and basophils. The same mediators as occur with true anaphylaxis are released and the same effects are produced. This reaction can happen, and often does, on initial as well as subsequent exposures, since no sensitization is required...
Interesting stuff.
On a side note, and this is really just nitpicking, but Dr. Strangelove, I beleive you have the dose of Epi wrong.
It is 0.15mg for pediatrics, and 0.3mg for adults initial dose. The 1mg dose is used for Cardiac Arrest...
Anyhoo.... I'd better get back to work.
-Xaque-